Bacterial Endotoxin (LAL) Testing

Bacterial endotoxin testing is performed on in vitro medical products that are in direct or indirect contact with cardiovascular, lymphatic and spinal fluid such as pacemakers and prostheses, pharmaceutical products used in the pharmaceutical industry and dialysis waters.

Endotoxin, a component of the outer membrane of the cells of Gram-negative bacteria, is lipopolysaccharide. Gram-negative bacteria can survive in environments such as water and air, even if the bacteria die. It is a pyrogen that can cause biological reactions if it enters the body in excess of a certain amount.

Escherichia coli, Proteus, Pseudomonas, Enterobacter and Klebsiella are some of the best known examples. Bacterial endotoxin test, also known as LAL determination, is one of the important checks for medical devices.

It is important to work with an expert team and competent laboratories in order to test and improve the quality and system performance of medical devices. As Nanolab Laboratories Group, we provide Bacterial Endotoxin (LAL) Testing services in Medical Devices.