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Analysis of Active Substance 2-Phenoxyethanol: Efficacy and Safety Assessment

In Which Products Is "2-phenoxyethanol" Found in Biocidal Products Used? What are its Effects?

Analysis of Active Substance 2-Phenoxyethanol: Efficacy and Safety Assessment

What is 2-phenoxyethanol?

2-phenoxyethanol is a colorless, oily liquid, slightly soluble in water, formed by the reaction of phenoxyethanol ethylene oxide and phenol. Generally used in cosmetic products, phenoxyethanol is also used in biocidal products.

Phenoxyethanol is a weak biocide. It is especially effective on gram negative bacteria, Pseudomonas aeruginosa strains. Phenoxyethanol used in anionic surfactant solutions can be a nutrient source for bacterial growth if it is not used in sufficient quantities. Generally, phenoxyethanol and p-hydroxybenzoic acid are used together to provide a broader antimicrobial effect.

2-Efficacy Evaluation of Phenoxyethanol

  • Bactericidal and Fungicidal Activity: It is effective against gram positive and gram negative bacteria, fungi and some viruses. Stops and destroys the growth of microorganisms by disrupting the cell membrane.
  • Effective Concentrations: Generally used in concentrations between 0.5-1.0%. Higher concentrations are generally unnecessary and may increase the risk of side effects.

The product types in which 2-phenoxyethanol can be used are specified as follows in Annex A - List of Substances with Product Type Identified in the scope of the “Biocidal Products Regulation”.

  • Product Type 1: Human hygiene
  • Product Type 2: Disinfectants and algicides not intended for direct application to humans or animals
  • Product Type 3: Animal hygiene
  • Product Type 4: Food and feed area
  • Product Type 6: Protect products during storage
  • Product Type 7: Film protectors
  • Product Type 10: Building material protectors
  • Product Type 11: Protectors for liquid coolant and processing systems
  • Product Type 13: Protectors for machining or cutting fluids

In conclusion; 2-Phenoxyethanol is an effective antimicrobial compound with a wide range of applications. However, accurate analysis methods and compliance with standards are critical for its safe and effective use. Sensitive techniques such as gas chromatography and HPLC provide active ingredient verification in both biocidal and cosmetic products. Their use within recommended limits in product formulations is important for both user safety and environmental impact.

Nano-lab Laboratories Group continues to provide services within the scope of Active Ingredient Analysis. We also provide services in Irritation Testing.

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